UPDATE 1-China rejects patent linked to Gilead hepatitis C drug

viernes 19 de junio de 2015 04:24 GYT

* Application for Sovaldi "prodrug" rejected

* Gilead still has China patent for active compound

* Follows India decision to reject application for Sovaldi

* Sovaldi controversial due to its high cost of $1,000 per pill (Recasts and writes through with details of the drug)

By Brendan Pierson and Adam Jourdan

NEW YORK/SHANGHAI, June 19 (Reuters) - China has rejected a Gilead Sciences Inc patent application related to its costly hepatitis C drug, a U.S. advocacy group said, adding the move may lead to other countries to consider rejecting patents for the controversial treatment.

Gilead has drawn fire for the cost of its top-selling drug Sovaldi, priced at $1,000 per pill in the United States or $84,000 for a typical 12-week course and its patents have been challenged in the U.S., India and Europe.

The application China has rejected was for a so-called prodrug, the inactive form of the drug which then converts into the chemically active compound once in the body, the New York-based Initiative for Medicines, Access & Knowledge (I-MAK) said.

Gilead, however, holds the China patent to the base compound in the drug, also known by its generic name sofosbuvir and China's rejection of the prodrug patent does not open the way for copycat drugs to be made in the world's No. 2 drug market.   Continuación...