* FTSEurofirst 300 down 1.3 pct after World Bank move
* Oil producers, miners lead declines amid commodities rout
* AstraZeneca bucks trend as blood-thinning drug hits goal
By Francesco Canepa
LONDON, Jan 14 (Reuters) - European shares fell at the open on Wednesday, mirroring a slump in copper and oil prices after the World Bank cut its global growth forecast for this year.
The FTSEurofirst 300 index of pan-European shares was down 1.3 percent at 1,357.56 points at 0818 GMT, erasing most of its advance since the start of the week.
Oil major Total and commodity firms Glencore and Rio Tinto were the biggest drags on the index as they fell between 3 percent and 8.8 percent.
The World Bank on Tuesday lowered its global growth forecast for 2015 and next year due to disappointing economic prospects in the euro zone, Japan and some major emerging economies that offset the benefit of lower oil prices.
"These growth fears are keeping markets busy and it is linked with the deflation question," said Christian Gattiker, chief strategist and head of research at Bank Julius Baer.
"We have the stress in financial markets because it's about the solvency and liquidity of oil producers."
A wave of stop-loss selling pushed London copper to 5-1/2 year lows on Wednesday, while Shanghai prices hit their 'limit down' after an oil rout slammed investment in commodities.
Shares in copper producer Antofagasta fell nearly 10 percent.
Pharma group AstraZeneca bucked the trend, rising 1.3 percent after its blood-thinning drug Brilinta cut hit a goal in a major clinical trial.
Europe bourses in 2014: link.reuters.com/pap87v
Asset performance in 2014: link.reuters.com/gap87v
Today's European research round-up (Editing by Gareth Jones)